Thursday, August 18, 2011

In the mammalian brain identified the cell-clock


In mammals the time "counts" the region of the brain called the suprachiasmatic nucleus. For years, biologists thought that cells within a day the department sent electrical signals quickly and slowly at night, which determines the course of circadian rhythms. All the internal processes of the body adjust to allegedly "beat" of the metronome.

British Bell Mine (Mino Belle) and Hugh Pidzhins ( Hugh Piggins ) decided to test the conjecture of their American counterparts. To do this, they gathered information about the sample excitation SCN-400 cells in mice. Then, the experimental data made ​​in the model, and it turned out that the assumptions and results actually observed processes coincide.

A more detailed study of such complex process will allow scientists to create a pill for insomnia and jet lag disorder in connection with the change of time zones. Perhaps the experts will also learn how to correct the work of the biological clock, and thus to treat diseases associated with inappropriate speed "chronometer":

Previously, biologists were shooting performance mixtures of these cells, hence the wrong conclusions about their work. Fordzher and his colleagues were able to drown out some and "hear" others.

The results showed that the active cells of the nucleus during the day are in an excited state, but emit electrical signals only for short periods at dawn and at sunset (but not always, as previously thought). This surge of brain sends to the rest of the body.

Despite the fact that the experiments involved only mice, the findings can be transferred to humans. For the "internal clock" of all mammals are similar (by the way, to confirm the results in humans does not work, because SCN is located deep in the brain and is not available for separate consideration.)

Read also about how the day artificially lengthened to 25 hours , were discovered 12-hour and 8-hour biological rhythms, and even the impact of the "internal clock" meal and blue light .

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